International Journal of Clinical Oncology and Cancer Research

Volume 2, Issue 2, April 2017

  • HER2 Dynamics: Advances in Breast Cancer Treatment

    Md Kamrul Hasan

    Issue: Volume 2, Issue 2, April 2017
    Pages: 29-30
    Received: 14 September 2016
    Accepted: 3 March 2017
    Published: 15 March 2017
    DOI: 10.11648/j.ijcocr.20170202.11
    Abstract: Breast cancer is one of the most deadly diseases all over the world. Recent findings suggest that HER2+ and HER2- Circulating Tumour Cells (CTCs) of metastatic breast cancer interconvert spontaneously and combined treatment with paclitaxel and Notch inhibitors achieves sustained suppression of tumorigenesis implicating novel therapeutic strategy to... Show More
  • Doxorubicin-Induced Cardiotoxicity: Molecular Mechanism and Protection by Conventional Drugs and Natural Products

    Hayder M. Alkuraishy, Ali I. Al-Gareeb, Hany Akeel Al-hussaniy

    Issue: Volume 2, Issue 2, April 2017
    Pages: 31-44
    Received: 9 February 2017
    Accepted: 1 March 2017
    Published: 20 March 2017
    DOI: 10.11648/j.ijcocr.20170202.12
    Abstract: Doxorubicin is useful anticancer drug because it's used in treatment of acute leukemia, Hodgkin's and non-Hodgkin's lymphomas, and many other malignant neoplasm. The mechanism of doxorubicin induce cardiotoxicity is multifactorial includes free radical stress, mitochondrial dysfunction and calcium overload these are the main causes of doxorubicin-i... Show More
  • The Influence of Serum Vitamin A on Lung Cancer Risk

    Erik Cook

    Issue: Volume 2, Issue 2, April 2017
    Pages: 45-50
    Received: 28 February 2017
    Accepted: 11 March 2017
    Published: 27 March 2017
    DOI: 10.11648/j.ijcocr.20170202.13
    Abstract: The objective of this study was to evaluate the association of serum level vitamin A with the incidence of lung cancer (LCa). An analysis, using a prospective study design, was conducted among a cohort of 3,086 men and women, ages 25 to 74 years, from the First National Health and Nutrition Examination Survey-Epidemiologic Follow-up Study. Using Co... Show More