Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024)

Conte Ibrahima; Sylla Abdoulaye; Soumah Aboubacar Fode Momo; Sylla Mohamed; Diallo Fatoumata Binta; Diallo Abdourahamane; Sy Telly; Keita Namory

doi:doi:10.11648/j.ijcocr.20251004.16

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Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024)

Conte Ibrahima^*

, Sylla Abdoulaye, Soumah Aboubacar Fode Momo, Sylla Mohamed, Diallo Fatoumata Binta, Diallo Abdourahamane, Sy Telly, Keita Namory

Published in International Journal of Clinical Oncology and Cancer Research (Volume 10, Issue 4)

Received: 26 October 2025 Accepted: 13 November 2025 Published: 29 December 2025

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Abstract

Introduction: Endometrial cancer is one of the most common gynaecological cancers. It mainly develops in postmenopausal women and is often diagnosed at a late stage. The aim of this study was to contribute to the study of endometrial cancers. Methods: This was a retrospective descriptive study covering a 10-year period (1 January 2015 to 31 December 2024) focusing on endometrial biopsy specimens and curettage samples received by the department during the study period. Results: Over a 10-year period, we collected 55 cases of endometrial cancer, representing 6.50% of uterine organic pathologies. Patients in the 60-70 age group were the most affected (34.54%). The average age was 46.2 years, with extremes of 29 and 86 years. The majority were nulliparous and primiparous in 34.54% and 25.45% of cases, respectively. Metrorrhagia was the main reason for consultation in 92.72% of cases. Biopsy was indicated for suspected endometrial cancer in 30.90% of cases. The samples examined were mainly from hysterectomy specimens (70.90%). Macroscopically, 60% of cases involved ulcerative-budding lesions and 65.45% involved diffuse localisation. Histologically, endometrioid carcinoma was the most common type (70.90%) and was limited to the myometrium in 46.15% of cases. Histological grades 2 and 3 were the most commonly observed, accounting for 27.27% and 54.54% of cases, respectively. Conclusion: Pathological examination is the only way to confirm a diagnosis of endometrial cancer. In order to limit the margin of diagnostic error, it is necessary to take a representative sample during the biopsy.

Published in	International Journal of Clinical Oncology and Cancer Research (Volume 10, Issue 4)
DOI	10.11648/j.ijcocr.20251004.16
Page(s)	167-171
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Endometrial Cancer, Pathological Anatomy, Conakry University Hospital, Guinea

1. Introduction

Endometrial cancer is a malignant tumour that develops from the lining of the uterus, known as the endometrium. It involves abnormal cell proliferation in the epithelial or connective tissue structures of this lining, with histological characteristics of malignancy

[1]

. This cancer is currently the most common gynaecological cancer in developed countries, surpassing even cervical cancer in some regions

[2]

The incidence of endometrial cancer is steadily increasing, particularly in relation to the ageing population and the rise in metabolic risk factors such as obesity, type 2 diabetes, and high blood pressure. In the United States, it was the fourth most common cancer in women in 2019, with approximately 61,880 new cases diagnosed and nearly 12,260 deaths attributed to this disease, according to the American Cancer Society

[2]

This cancer mainly affects postmenopausal women, with a median age at diagnosis of 61 years. Approximately 92% of cases occur in patients over the age of 50

[3]

. In Africa, particularly in Guinea, epidemiological data are still limited, but an upward trend in the incidence of this disease has been observed in gynaecology and pathology departments, due in particular to improved access to diagnosis and treatment.

Histologically, more than 90% of endometrial cancers are epithelial in origin. Endometrioid adenocarcinomas are the most common form, but other more aggressive histological types may be encountered, such as serous carcinomas, clear cell carcinomas, carcinosarcomas (or mixed malignant Müllerian tumours) and, more rarely, stromal sarcomas

[3]

In a context of limited resources such as in Guinea, histology is an essential diagnostic tool for characterising suspicious endometrial lesions, guiding therapeutic management and establishing a prognosis. However, consultation delays, low patient awareness and diagnostic delays remain major challenges in local health facilities.

This study aims to investigate the epidemiological, clinical, and anatomopathological aspects of endometrial cancer diagnosed in the pathology department of the Conakry University Hospital over a ten-year period (2015–2024). Specifically, it aims to determine the frequency of endometrial cancer among uterine pathologies observed at the Conakry University Hospital, describe the sociodemographic and clinical profile of patients with endometrial cancer, and analyse the anatomopathological characteristics of endometrial cancers (histological type, location, macroscopic appearance, and grade).

2. Patients and Methods

Type, period and location of the study: this is a retrospective descriptive study, conducted over a period of ten (10) years, from 1 January 2015 to 31 December 2024, carried out in the pathology department of the Conakry University Hospital.

Study population: The study included all patients who underwent histological examination of the endometrium during the study period and who were diagnosed with endometrial cancer based on histological findings.

Inclusion criteria: All women who underwent endometrial sampling (biopsy, curettage, surgical specimen) were included in the study, provided that the sample resulted in a histological diagnosis confirming a malignant endometrial tumour and that the files contained usable clinical data.

Exclusion criteria: cases of benign tumours or non-atypical hyperplasia, incomplete or unusable records (absence of histological report or insufficient clinical data) and poorly preserved or uninterpretable samples were excluded from the study.

Variables studied: The variables studied included: sociodemographic data (age, menopausal status, parity, etc.), clinical data (symptoms, medical and family history, risk factors), paraclinical data (type of sample, time to consultation), and histopathological data (histological type of cancer, grade).

Data collection and analysis: Data were collected from the pathology laboratory records and patients' medical files. They were entered and analysed using statistical software (e.g. SPSS or Excel, depending on available resources). The results were expressed as frequencies, percentages, means and standard deviations.

Ethical considerations: the collection tools and anonymously collected information remain strictly protected from any disclosure and will be used solely for scientific purposes.

Limitations of the study: the main limitations lie in its retrospective nature, the absence of immunohistochemical and imaging data (magnetic resonance imaging, ultrasound), and the sometimes incomplete quality of clinical records. These factors may have restricted the interpretation of certain prognostic parameters.

3. Results

Text1: Frequency of endometrial cancer compared to other uterine pathologies

During the study period (2015–2024), out of a total of 846 histological samples taken for uterine organic pathologies recorded in the department, 55 cases of endometrial cancer were diagnosed, representing a frequency of 6.50%.

Table 1. Distribution of cases by year of study.

Year	Number (N=55)	%
2015	03	5.4
2016	02	3.6
2017	04	7.3
2018	04	7.3
2019	03	5.4
2020	04	7.3
2021	06	10.9
2022	07	12.7
2023	10	18.2
2024	12	21.8
Total	55	100

Table 2. Distribution of patients according to age and parity.

	Number (N=55)	%
Age
<30	01	1.8
30-39	03	5.5
40-49	03	5.5
50-59	08	14.5
60-69	19	34.5
70-79	14	25.5
>79	07	12.7
Parity
Nulliparous	19	34.5
Primiparous	14	25.5
Paucipara	10	18.2
Multipara	12	21.8

The age of the patients ranged from under 30 to over 79. The most represented age group was 60–69 (34.5%), followed by 70–79 (25.5%). Over 70% of patients were over 60 years old. Nulliparous and primiparous women were the most affected, at 34.5% and 25.5% respectively.

Table 3. Frequency of patients according to reasons for consultation and initial clinical diagnosis.

	Number (N=55)	%
Reason for consultation
Abdominal and pelvic pain	47	85.5
Abdominal mass	43	78.2
Leucorrhoea	27	49.1
Metrorrhagia	51	92,7
Hydrorrhoea	50	90,9
Initial clinical diagnosis
Endometrial cancer	17	30.9
Endometrial tumour	14	25.4
Uterine tumour	09	16.4
Endometrial hyperplasia	15	27.3
Type of sample
Curettage core sample	15	27.2
Hysterectomy	39	71.0
Hysteroscopic biopsy core sample	01	1.8

Metrorrhagia was the main reason for consultation in 92.7% of cases.

Endometrial cancer was clinically suspected in 30.90% of cases.

Hysterectomy specimens accounted for the majority of samples analysed (71.0%), followed by curettage cores (27.2%).

Table 4. Distribution of cases according to anatomical pathology aspects.

	Number (N=55)	%
Seat
Diffuse	36	65.5
Uterine fundus	04	7.3
Right horn	01	1.8
Left horn	02	3.6
Isthmus	01	1.8
Anterior surface	06	11.0
Posterior surface	05	9.0
Macroscopic appearance
Buddling	08	14.5
Ulcerative-budding	33	60.0
Ulcerative	09	16.4
Infiltrative	05	9.1
Histological type or microscopy
Endometrioid adenocarcinoma (Type 1)	39	71.0
Clear cell adenocarcinoma	08	14.5
Sarcoma	02	3.6
Carcinosarcoma	01	1.8
Lymphoma	02	3.6
Metastasis	03	5.5
Histological grade
Grade 1	10	18.2
Grade 2	15	27.3
Grade 3	30	54.5

In 65.5% of cases, the location was diffuse. Segmental locations (fundus, anterior or posterior wall, uterine horns) were less common.

The ulcerative-budding appearance was predominant (60%), followed by ulcerated forms (16.36%) and isolated budding forms (14.5%). The most dominant histological type was type I endometrioid adenocarcinoma (70.9%). Histological grades 2 and 3 were the most commonly observed, at 27.27% and 54.54% respectively.

4. Discussions

This retrospective study conducted over a 10-year period at the Conakry University Hospital identified 55 cases of endometrial cancer, confirmed by histopathological examination. This frequency is consistent with the observations of Manfredi et al.

[4]

and Taieb et al.

[5]

, who report similar rates in comparable cohorts. However, it differs from those reported by Kinkel et al.

[6]

and Rieck. GC. et al

[7]

, who found 5.2% and 4.2% respectively.

These results highlight the importance of histological diagnosis in identifying uterine cancers, which are often detected at an advanced stage.

The number of cases has increased over the years, with a peak observed in 2024. This trend can be explained by improved screening, better access to pathology services, or a real increase in incidence.

The majority of patients were over 60 years of age, with a peak between 60 and 69 years (34.5%), which is consistent with data in the literature

[8, 9]

. The higher average age compared to some studies could be attributed to delayed diagnosis or poor access to specialised care in Guinea.

Nulliparous and primiparous women were the most represented, confirming the well-established association between nulliparity and endometrial cancer

[5, 10]

. This factor is linked to prolonged exposure to oestrogen without the counterbalancing effect of progesterone.

Postmenopausal metrorrhagia was the main reason for consultation (92.7%), followed by hydrorrhoea. These results are consistent with those reported by Rieck et al.

[7]

, Mariani et al.

[11]

, and Taieb et al.

[5]

, who identify metrorrhagia as a cardinal symptom of endometrial cancer. However, Creasman. WT. et al

[12]

found that endometrial cancers were more often revealed by menometrorrhagia and hydrorrhoea in 95% of cases. Our results were contrary to those of Hidaka. T., et al

[13]

, who found that hydrorrhoea consisting of foul-smelling, sometimes bloody fluid was the most commonly reported symptom in 75% of cases.

The histological diagnosis was mainly established on the basis of hysterectomy specimens (70.90%), suggesting that many cases were discovered at an advanced stage, requiring radical surgical treatment. This predominance of surgical specimens is similar to that reported by Raoudha et al.

[14]

The lesions were often diffuse (65.5%) and presented an ulcerative-budding appearance in 60% of cases, which is consistent with the descriptions by La Russa et al.

[15]

and Leblanc et al.

[16]

Type 1 endometrioid adenocarcinoma was the predominant histological type in our study, as is typically observed by authors

[6, 7, 14]

. Aggressive histological types (carcinosarcomas, lymphomas, sarcomas) were rare.

However, high histological grades (2 and 3) indicate significant tumour aggressiveness. Peignaux. K., et al

[17]

, who found 38.9% grade 2 and Poitreau. Y., et al

[18]

50% grade 1.

5. Conclusion

Although less common than other gynaecological cancers, endometrial cancer remains a significant entity in our practice. It mainly affects older women, predominantly nulliparous women, and the most common reason for consultation is metrorrhagia.

Type 1 endometrioid adenocarcinomas are the most common, often invasive and sometimes high-grade, which complicates management.

Our study highlights the need to strengthen early screening, collaboration between specialists and access to paraclinical examinations (ultrasound, hysteroscopy, immunohistochemistry) for better management.

Finally, further research is needed to better understand and treat this cancer in Guinea.

Abbreviations

Nomber

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Boronow RC, Morrow CP, Creasman WT, Disaia PJ, Silverberg SG, Miller A, et al. Surgical staging in endometrial cancer: clinicalpat hologic findings of a prosp ective study. Obstet Gynecol 2014; 63: 82 5-32.
[2]	Larson DM, Connor GP, Broste SK, Krawisz BR, Johnson KK. Prognostic sign ificance of gross myometrial invasion with endometrial cancer. Obstet Gynecol 2016; 88: 394-8.
[3]	Kodama S, Kase H, Tanaka K, Matsui K. Multivariate analysis of prognostic factors in patients with endometrial cancer. Int J Gynae col Obstet 2016; 53: 23-30.
[4]	Manfredi R, Mirk P, Maresca G, Margariti PA, Testa A, Zannoni GF, et al. Local regional staging of endometrial carcinoma: role of MR imaging in surgical planning. Radiology 2014; 231: 372-8.
[5]	Taïeb S, Ceugnart L, Leblanc E, Chevalier A, Cabaret V, Querleu D. MR Imaging of endometrial carcinoma: role and limits. Bull Can cer 2012; 89: 963-8.
[6]	Kinkel K, Kaji Y, Kyle K. et al. Radiologic staging in patients with endometrial cancer: a meta-analysis. Radiology 2019; 22: 71-78.
[7]	Rieck GC, Bulman J, Whitaker R, Leeson SC. A retrospective revi ew of magnetic resonance imaging in assessing the extent of myom etrial infiltration for patients with endometrial carcinoma. J Obstet Gynaecol 2015; 25: 765-8.
[8]	Nasi F, Fiocchi F, Pecchi A, Rivasi F, Torricelli P. MRI evaluation of myometrial invasion by endometrial carcinoma. Comparison between fast-spin-echo T2w and coronal-FMPSPGR Gadolinium-Dota-enhanced sequences. Radiol Med (Torino) 2015; 110: 199-210.
[9]	Utsunomiya D, Notsute S, Hayashida Y, Lwakatare F, Katabuchi H, Okamura H, et al. Endometrial carcinoma in adenomyosis: assess ment of myometrial invasion on T2-weighted spin-echo and gadolinum-enhanced T1-weighted images. Am J Roentgenol 2014; 182: 399-404.
[10]	Narducci F, Lambaudie E, Sonoda Y, et al. Endometrial cancer: what’s new? Gynecol Obstet Fertil 2013; 31: 581-96.
[11]	Mariani A, Keeney GL, Aletti G, Webb MJ, Haddock MG, PodratzKC. Endom etrialcarcinoma: paraaorticdissemination. Gynecol Oncol 2014; 92: 833-8. 8.
[12]	Creasman WT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Heller PB. Surgical pathologic spread patterns of endometrial cancer. A gynecologic oncology group study. Cancer 1987; 60(8 suppl.): 2015-41.
[13]	Hidaka T, Kato K, Yonezawa R, et al. Omission of lymphadenectomy is possible for low-risk corpus cancer. Eur J Surg Oncol 2017; 33: 86-90.
[14]	Raoudha Doghri, Yosra Yahyaoui, Azza Gabsi, Maha Driss, Nadia Boujelbene, Lamia Charfi, Mezlini Amel et coll: Les carci nomes de l’endomètre: Etude anatomopathologique et histopronos tique à propos de 62 cas dans un centre du nord tunisien: Elsevier Masson 2017.12.20-27.
[15]	La Russa. M., Zapardiel. I., Halaska. MI., et coll: Prise en charge conservatrice du cancer de l’endomètre: une enquête auprès de cliniciens européens: Published online Juin 2018; 4820-7.
[16]	Leblanc. E., V. Samouelian, L. Boulanger, F. Narducci: Ya-t-il encore des contre-indications à la laparoscopie dans le traitement chirurgical des cancers de l’endomètre ? Elsevier Masson 2015; (38): 119-125.
[17]	Peignaux. K., Truc. G., Blanchard. N., Créhange. G., et coll. Maingon: Cancer de l’endomètre dé stade 1: Elsevier Masson 2018(12): 625-629.
[18]	Pointreau. Y., Bernadou. G, Denis. F., Barillot. I. J. Cancer de l’endomètre: Elsevier Masson 2016; 34: 154-160.

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Ibrahima, C., Abdoulaye, S., Momo, S. A. F., Mohamed, S., Binta, D. F., et al. (2025). Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). International Journal of Clinical Oncology and Cancer Research, 10(4), 167-171. https://doi.org/10.11648/j.ijcocr.20251004.16

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Ibrahima, C.; Abdoulaye, S.; Momo, S. A. F.; Mohamed, S.; Binta, D. F., et al. Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). Int. J. Clin. Oncol. Cancer Res. 2025, 10(4), 167-171. doi: 10.11648/j.ijcocr.20251004.16

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Ibrahima C, Abdoulaye S, Momo SAF, Mohamed S, Binta DF, et al. Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). Int J Clin Oncol Cancer Res. 2025;10(4):167-171. doi: 10.11648/j.ijcocr.20251004.16

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@article{10.11648/j.ijcocr.20251004.16,
  author = {Conte Ibrahima and Sylla Abdoulaye and Soumah Aboubacar Fode Momo and Sylla Mohamed and Diallo Fatoumata Binta and Diallo Abdourahamane and Sy Telly and Keita Namory},
  title = {Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024)},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {10},
  number = {4},
  pages = {167-171},
  doi = {10.11648/j.ijcocr.20251004.16},
  url = {https://doi.org/10.11648/j.ijcocr.20251004.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20251004.16},
  abstract = {Introduction: Endometrial cancer is one of the most common gynaecological cancers. It mainly develops in postmenopausal women and is often diagnosed at a late stage. The aim of this study was to contribute to the study of endometrial cancers. Methods: This was a retrospective descriptive study covering a 10-year period (1 January 2015 to 31 December 2024) focusing on endometrial biopsy specimens and curettage samples received by the department during the study period. Results: Over a 10-year period, we collected 55 cases of endometrial cancer, representing 6.50% of uterine organic pathologies. Patients in the 60-70 age group were the most affected (34.54%). The average age was 46.2 years, with extremes of 29 and 86 years. The majority were nulliparous and primiparous in 34.54% and 25.45% of cases, respectively. Metrorrhagia was the main reason for consultation in 92.72% of cases. Biopsy was indicated for suspected endometrial cancer in 30.90% of cases. The samples examined were mainly from hysterectomy specimens (70.90%). Macroscopically, 60% of cases involved ulcerative-budding lesions and 65.45% involved diffuse localisation. Histologically, endometrioid carcinoma was the most common type (70.90%) and was limited to the myometrium in 46.15% of cases. Histological grades 2 and 3 were the most commonly observed, accounting for 27.27% and 54.54% of cases, respectively. Conclusion: Pathological examination is the only way to confirm a diagnosis of endometrial cancer. In order to limit the margin of diagnostic error, it is necessary to take a representative sample during the biopsy.},
 year = {2025}
}

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TY - JOUR
T1 - Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024)
AU - Conte Ibrahima
AU - Sylla Abdoulaye
AU - Soumah Aboubacar Fode Momo
AU - Sylla Mohamed
AU - Diallo Fatoumata Binta
AU - Diallo Abdourahamane
AU - Sy Telly
AU - Keita Namory
Y1 - 2025/12/29
PY - 2025
N1 - https://doi.org/10.11648/j.ijcocr.20251004.16
DO - 10.11648/j.ijcocr.20251004.16
T2 - International Journal of Clinical Oncology and Cancer Research
JF - International Journal of Clinical Oncology and Cancer Research
JO - International Journal of Clinical Oncology and Cancer Research
SP - 167
EP - 171
PB - Science Publishing Group
SN - 2578-9511
UR - https://doi.org/10.11648/j.ijcocr.20251004.16
AB - Introduction: Endometrial cancer is one of the most common gynaecological cancers. It mainly develops in postmenopausal women and is often diagnosed at a late stage. The aim of this study was to contribute to the study of endometrial cancers. Methods: This was a retrospective descriptive study covering a 10-year period (1 January 2015 to 31 December 2024) focusing on endometrial biopsy specimens and curettage samples received by the department during the study period. Results: Over a 10-year period, we collected 55 cases of endometrial cancer, representing 6.50% of uterine organic pathologies. Patients in the 60-70 age group were the most affected (34.54%). The average age was 46.2 years, with extremes of 29 and 86 years. The majority were nulliparous and primiparous in 34.54% and 25.45% of cases, respectively. Metrorrhagia was the main reason for consultation in 92.72% of cases. Biopsy was indicated for suspected endometrial cancer in 30.90% of cases. The samples examined were mainly from hysterectomy specimens (70.90%). Macroscopically, 60% of cases involved ulcerative-budding lesions and 65.45% involved diffuse localisation. Histologically, endometrioid carcinoma was the most common type (70.90%) and was limited to the myometrium in 46.15% of cases. Histological grades 2 and 3 were the most commonly observed, accounting for 27.27% and 54.54% of cases, respectively. Conclusion: Pathological examination is the only way to confirm a diagnosis of endometrial cancer. In order to limit the margin of diagnostic error, it is necessary to take a representative sample during the biopsy.
VL - 10
IS - 4
ER -

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Author Information

Conte Ibrahima

Department of Obstetrics and Gynaecology, Ignace Deen National Hospital, Conakry, Guinea

Contact Email

http://orcid.org/0009-0007-5466-8574
Sylla Abdoulaye

Department of Pathological Anatomy and Cytology, Donka National Hospital, Conakry, Guinea
Soumah Aboubacar Fode Momo

Department of Obstetrics and Gynaecology, Ignace Deen National Hospital, Conakry, Guinea
Sylla Mohamed

Department of Pathological Anatomy and Cytology, Donka National Hospital, Conakry, Guinea
Diallo Fatoumata Binta

Department of Pathological Anatomy and Cytology, Donka National Hospital, Conakry, Guinea
Diallo Abdourahamane

Department of Obstetrics and Gynaecology, Ignace Deen National Hospital, Conakry, Guinea
Sy Telly

Department of Obstetrics and Gynaecology, Ignace Deen National Hospital, Conakry, Guinea
Keita Namory

Department of Obstetrics and Gynaecology, Donka National Hospital, Conakry, Guinea

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Ibrahima, C., Abdoulaye, S., Momo, S. A. F., Mohamed, S., Binta, D. F., et al. (2025). Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). International Journal of Clinical Oncology and Cancer Research, 10(4), 167-171. https://doi.org/10.11648/j.ijcocr.20251004.16

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Ibrahima, C.; Abdoulaye, S.; Momo, S. A. F.; Mohamed, S.; Binta, D. F., et al. Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). Int. J. Clin. Oncol. Cancer Res. 2025, 10(4), 167-171. doi: 10.11648/j.ijcocr.20251004.16

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Ibrahima C, Abdoulaye S, Momo SAF, Mohamed S, Binta DF, et al. Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024). Int J Clin Oncol Cancer Res. 2025;10(4):167-171. doi: 10.11648/j.ijcocr.20251004.16

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@article{10.11648/j.ijcocr.20251004.16,
  author = {Conte Ibrahima and Sylla Abdoulaye and Soumah Aboubacar Fode Momo and Sylla Mohamed and Diallo Fatoumata Binta and Diallo Abdourahamane and Sy Telly and Keita Namory},
  title = {Endometrial Cancer in the Pathological Anatomy Department of the Conakry University Hospital (Guinea): 55 Cases over 10 Years (2015–2024)},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {10},
  number = {4},
  pages = {167-171},
  doi = {10.11648/j.ijcocr.20251004.16},
  url = {https://doi.org/10.11648/j.ijcocr.20251004.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20251004.16},
  abstract = {Introduction: Endometrial cancer is one of the most common gynaecological cancers. It mainly develops in postmenopausal women and is often diagnosed at a late stage. The aim of this study was to contribute to the study of endometrial cancers. Methods: This was a retrospective descriptive study covering a 10-year period (1 January 2015 to 31 December 2024) focusing on endometrial biopsy specimens and curettage samples received by the department during the study period. Results: Over a 10-year period, we collected 55 cases of endometrial cancer, representing 6.50% of uterine organic pathologies. Patients in the 60-70 age group were the most affected (34.54%). The average age was 46.2 years, with extremes of 29 and 86 years. The majority were nulliparous and primiparous in 34.54% and 25.45% of cases, respectively. Metrorrhagia was the main reason for consultation in 92.72% of cases. Biopsy was indicated for suspected endometrial cancer in 30.90% of cases. The samples examined were mainly from hysterectomy specimens (70.90%). Macroscopically, 60% of cases involved ulcerative-budding lesions and 65.45% involved diffuse localisation. Histologically, endometrioid carcinoma was the most common type (70.90%) and was limited to the myometrium in 46.15% of cases. Histological grades 2 and 3 were the most commonly observed, accounting for 27.27% and 54.54% of cases, respectively. Conclusion: Pathological examination is the only way to confirm a diagnosis of endometrial cancer. In order to limit the margin of diagnostic error, it is necessary to take a representative sample during the biopsy.},
 year = {2025}
}

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