Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women

Mwenze Didier; Kyabu Véronique; Mulenga Philippe; Mukalay Abdon; Chola Joseph; Kalenga Prosper; Ilunga Julien

doi:doi:10.11648/j.ijcocr.20190401.11

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Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women

Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, Kalenga Prosper, Ilunga Julien

Published in International Journal of Clinical Oncology and Cancer Research (Volume 4, Issue 1)

Received: 28 March 2019 Accepted: 5 May 2019 Published: 30 May 2019

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Abstract

The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.

Published in	International Journal of Clinical Oncology and Cancer Research (Volume 4, Issue 1)
DOI	10.11648/j.ijcocr.20190401.11
Page(s)	1-4
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Papillomavirus, Intra Epithelial Neoplasia, Cervix, Lubumbashi

References

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APA Style

Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. (2019). Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. International Journal of Clinical Oncology and Cancer Research, 4(1), 1-4. https://doi.org/10.11648/j.ijcocr.20190401.11

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ACS Style

Mwenze Didier; Kyabu Véronique; Mulenga Philippe; Mukalay Abdon; Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int. J. Clin. Oncol. Cancer Res. 2019, 4(1), 1-4. doi: 10.11648/j.ijcocr.20190401.11

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AMA Style

Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int J Clin Oncol Cancer Res. 2019;4(1):1-4. doi: 10.11648/j.ijcocr.20190401.11

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@article{10.11648/j.ijcocr.20190401.11,
  author = {Mwenze Didier and Kyabu Véronique and Mulenga Philippe and Mukalay Abdon and Chola Joseph and Kalenga Prosper and Ilunga Julien},
  title = {Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {4},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.ijcocr.20190401.11},
  url = {https://doi.org/10.11648/j.ijcocr.20190401.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20190401.11},
  abstract = {The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.},
 year = {2019}
}

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TY  - JOUR
T1  - Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women
AU  - Mwenze Didier
AU  - Kyabu Véronique
AU  - Mulenga Philippe
AU  - Mukalay Abdon
AU  - Chola Joseph
AU  - Kalenga Prosper
AU  - Ilunga Julien
Y1  - 2019/05/30
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcocr.20190401.11
DO  - 10.11648/j.ijcocr.20190401.11
T2  - International Journal of Clinical Oncology and Cancer Research
JF  - International Journal of Clinical Oncology and Cancer Research
JO  - International Journal of Clinical Oncology and Cancer Research
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2578-9511
UR  - https://doi.org/10.11648/j.ijcocr.20190401.11
AB  - The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.
VL  - 4
IS  - 1
ER  -

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Author Information

Mwenze Didier

Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kyabu Véronique

Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Mulenga Philippe

Public Health Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Mukalay Abdon

Public Health Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Chola Joseph

Gynecology Obstetrics Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kalenga Prosper

Gynecology Obstetrics Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Ilunga Julien

Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

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APA Style

Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. (2019). Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. International Journal of Clinical Oncology and Cancer Research, 4(1), 1-4. https://doi.org/10.11648/j.ijcocr.20190401.11

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ACS Style

Mwenze Didier; Kyabu Véronique; Mulenga Philippe; Mukalay Abdon; Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int. J. Clin. Oncol. Cancer Res. 2019, 4(1), 1-4. doi: 10.11648/j.ijcocr.20190401.11

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AMA Style

Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int J Clin Oncol Cancer Res. 2019;4(1):1-4. doi: 10.11648/j.ijcocr.20190401.11

Copy | Download

@article{10.11648/j.ijcocr.20190401.11,
  author = {Mwenze Didier and Kyabu Véronique and Mulenga Philippe and Mukalay Abdon and Chola Joseph and Kalenga Prosper and Ilunga Julien},
  title = {Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {4},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.ijcocr.20190401.11},
  url = {https://doi.org/10.11648/j.ijcocr.20190401.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20190401.11},
  abstract = {The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.},
 year = {2019}
}

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TY  - JOUR
T1  - Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women
AU  - Mwenze Didier
AU  - Kyabu Véronique
AU  - Mulenga Philippe
AU  - Mukalay Abdon
AU  - Chola Joseph
AU  - Kalenga Prosper
AU  - Ilunga Julien
Y1  - 2019/05/30
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcocr.20190401.11
DO  - 10.11648/j.ijcocr.20190401.11
T2  - International Journal of Clinical Oncology and Cancer Research
JF  - International Journal of Clinical Oncology and Cancer Research
JO  - International Journal of Clinical Oncology and Cancer Research
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2578-9511
UR  - https://doi.org/10.11648/j.ijcocr.20190401.11
AB  - The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.
VL  - 4
IS  - 1
ER  -

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